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In my Front-end Architectural work on restructuring/rebuilding/refining our biggest site (due early 2007) I have used the Yahoo Graded Browser Support as a guide for which browsers to target and how to make QA easier. I find Yahoos solution to this everlasting problem very professional and usable for an organisation.
Front-End Book is run and primarily written by Mattias Hising, an experienced Lead Developer from Uppsala, Sweden. I try to focus my efforts on Front-End related issues, as I find the problems to solve are more complex and interesting than the ones in traditional back-end development.